Biochemical Premotor Biomarkers for Parkinson's Disease
Identifieur interne : 001193 ( Main/Exploration ); précédent : 001192; suivant : 001194Biochemical Premotor Biomarkers for Parkinson's Disease
Auteurs : Brit Mollenhauer [Allemagne] ; JING ZHANG [États-Unis]Source :
- Movement disorders [ 0885-3185 ] ; 2012.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
A biomarker is a biological characteristic that is objectively measured and evaluated as an indicator of normal biological or pathologic processes or of pharmacologic responses to a therapeutic intervention. We reviewed the current status of target protein biomarkers (eg, total/oligomeric α-synuclein and DJ-1) in cerebrospinal fluid, as well as on unbiased processes that can be used to discover novel biomarkers. We have also provide ddetails about strategies toward potential populations/models and technologies, including the need for standardized sampling techniques, to pursue the identification of new biochemical markers in the premotor stage of Parkinson's disease in the future.
Affiliations:
- Allemagne, États-Unis
- District de Kassel, Hesse (Land), Washington (État)
- Cassel (Hesse), Seattle
- Université de Washington
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000198
- to stream PascalFrancis, to step Curation: 002B16
- to stream PascalFrancis, to step Checkpoint: 000266
- to stream Main, to step Merge: 001245
- to stream Main, to step Curation: 001193
Le document en format XML
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We reviewed the current status of target protein biomarkers (eg, total/oligomeric α-synuclein and DJ-1) in cerebrospinal fluid, as well as on unbiased processes that can be used to discover novel biomarkers. We have also provide ddetails about strategies toward potential populations/models and technologies, including the need for standardized sampling techniques, to pursue the identification of new biochemical markers in the premotor stage of Parkinson's disease in the future.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>États-Unis</li></country><region><li>District de Kassel</li><li>Hesse (Land)</li><li>Washington (État)</li></region><settlement><li>Cassel (Hesse)</li><li>Seattle</li></settlement><orgName><li>Université de Washington</li></orgName></list><tree><country name="Allemagne"><region name="Hesse (Land)"><name sortKey="Mollenhauer, Brit" sort="Mollenhauer, Brit" uniqKey="Mollenhauer B" first="Brit" last="Mollenhauer">Brit Mollenhauer</name></region></country><country name="États-Unis"><region name="Washington (État)"><name sortKey="Jing Zhang" sort="Jing Zhang" uniqKey="Jing Zhang" last="Jing Zhang">JING ZHANG</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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